Gary Schindelman

Dr. Schindelman was the recipient of the 2015 Donald R. Loftsgordon Memorial Award for Outstanding Teaching.

Courses

Molecular Biology (Bio221).  This course focuses on understanding the processes in a cell at a molecular level that transfer information from genetic information through the expression of functional proteins. Topics include: Basic structure of DNA RNA and Proteins; gene structure; chromosomal organization; genomic structure and organization; DNA replication; transcription translation and processing of gene products; molecular regulation of gene expression mechanisms in prokaryotes and eukaryotes; regulatory and catalytic RNA including siRNA and miRNA; and the techniques to study these processes.

Principles of Biochemistry (Bio322).  Survey of the basic principles that power biological processes in all living organisms. Includes introduction to biochemical techniques enzyme structure and function intermediary metabolism synthesis and degradation of biological macromolecules information transfer and a concept-driven integration of these subjects into a biological context.

Biochemistry I (Bio349).  This course explores the roles of the essential biological macromolecules focusing on proteins while covering lipids carbohydrates and nucleic acids. Topics include the structure and function of these macromolecules as well as an investigation of the biochemical methods used to study them. Also included are topics covering proteomics DNA-based information technologies biosignaling and an introduction to enzyme kinetics.

Publications

* denotes undergraduate author

Howe KL, Bolt BJ, Cain S, Chan J, Chen WJ, Davis P, Done J, Down T, Gao S, Grove C, Harris TW, Kishore R, Lee R, Lomax J, Li Y, Muller HM, Nakamura C, Nuin P, Paulini M, Raciti D, Schindelman G, Stanley E, Tuli MA, Van Auken K, Wang D, Wang X, Williams G, Wright A, Yook K, Berriman M, Kersey P, Schedl T, Stein L, Sternberg PW. WormBase 2016: expanding to enable helminth genomic research. Nucleic Acids Res. 2016 Jan 4;44(D1):D774-80.

Valk J*, Schindelman G, Martin GG. The peritrophic membrane of the gastropod Megathura crenulata: structure, composition, and site of formation. Invertebrate Biology. 2014 June; 133(2):136–145

Harris TW, Baran J, Bieri T, Cabunoc A, Chan J, Chen WJ, Davis P, Done J, Grove C, Howe K, Kishore R, Lee R, Li Y, Muller HM, Nakamura C, Ozersky P, Paulini M, Raciti D, Schindelman G, Tuli MA, Auken KV, Wang D, Wang X, Williams G, Wong JD, Yook K, Schedl T, Hodgkin J, Berriman M, Kersey P, Spieth J, Stein L, Sternberg PW. WormBase 2014: new views of curated biology. Nucleic Acids Res. 2014 Jan 1;42(1):D789-93.

Fang R, Schindelman G, Van Auken K, Fernandes J, Chen W, Wang X, Davis P, Tuli MA, Marygold SJ, Millburn G, Matthews B, Zhang H, Brown N, Gelbart WM, Sternberg PW. Automatic categorization of diverse experimental information in the bioscience literature. BMC Bioinformatics. 2012 Jan 26;13:16.

Yook K, Harris TW, Bieri T, Cabunoc A, Chan J, Chen WJ, Davis P, de la Cruz N, Duong A, Fang R, Ganesan U, Grove C, Howe K, Kadam S, Kishore R, Lee R, Li Y, Muller HM, Nakamura C, Nash B, Ozersky P, Paulini M, Raciti D, Rangarajan A, Schindelman G, Shi X, Schwarz EM, Ann Tuli M, Van Auken K, Wang D, Wang X, Williams G, Hodgkin J, Berriman M, Durbin R, Kersey P, Spieth J, Stein L, Sternberg PW. WormBase 2012: more genomes, more data, new website. Nucleic Acids Res. 2012 Jan;40(Database issue):D735-41.

Schindelman G, Fernandes JS, Bastiani CA, Yook K, Sternberg PW. Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community. BMC Bioinformatics. 2011 Jan 24;12:32.

Harris TW, Antoshechkin I, Bieri T, Blasiar D, Chan J, Chen WJ, De La Cruz N, Davis P, Duesbury M, Fang R, Fernandes J, Han M, Kishore R, Lee R, Müller HM, Nakamura C, Ozersky P, Petcherski A, Rangarajan A, Rogers A, Schindelman G, Schwarz EM, Tuli MA, Van Auken K, Wang D, Wang X, Williams G, Yook K, Durbin R, Stein LD, Spieth J, Sternberg PW. WormBase: a comprehensive resource for nematode research. Nucleic Acids Research 2010 Jan;38 (Database issue) D463-7

Rogers A, Antoshechkin I, Bieri T, Blasiar D, Bastiani C, Canaran P, Chan J, Chen WJ, Davis P, Fernandes J, Fiedler TJ, Han M, Harris TW, Kishore R, Lee R, McKay S, Müller HM, Nakamura C, Ozersky P, Petcherski A, Schindelman G, Schwarz EM, Spooner W, Tuli MA, Van Auken K, Wang D, Wang X, Williams G, Yook K, Durbin R, Stein LD, Spieth J, Sternberg PW. WormBase 2007. Nucleic Acids Research 2008 Jan;36 (Database issue) D612-7

Karbowski J, Schindelman G, Cronin CJ, Seah A, Sternberg PW. Systems level circuit model of C. elegans undulatory locomotion: mathematical modeling and molecular genetics. Journal of Computational Neuroscience 2008 Jun;24(3): 253-76.

Bieri T, Blasiar D, Ozersky P, Antoshechkin I, Bastiani C, Canaran P, Chan J, Chen N, Chen WJ, Davis P, Fiedler TJ, Girard L, Han M, Harris TW, Kishore R, Lee R, McKay S, Muller HM, Nakamura C, Petcherski A, Rangarajan A, Rogers A, Schindelman G, Schwarz EM, Spooner W, Tuli MA, Van Auken K, Wang D, Wang X, Williams G, Durbin R, Stein LD, Sternberg PW, Spieth J. WormBase: new content and better access. Nucleic Acids Research 2007 Jan;35 (Database issue)

Schindelman G, Whittaker AJ, Thum JY*, Gharib S, Sternberg PW. Initiation of male sperm-transfer behavior in Caenorhabditis elegans requires input from the ventral nerve cord. BMC Biology 2006 Aug 15;4:26.

Roudier F, Fernandez AG, Fujita M, Himmelspach R, Borner GH, Schindelman G, Song S, Baskin TI, Dupree P, Wasteneys GO, and Benfey P. COBRA, an Arabidopsis Extracellular Glycosylphosphatidylinositol-Anchored Protein, Specifically Controls Highly Anisotropic Expansion through Its Involvement in Cellulose Microfibril Orientation. Plant Cell 2005 Apr 22.

Roudier F, Schindelman G, DeSalle R, Benfey PN. The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion. Plant Physiology 2002 Oct;130(2):538-48.

Schindelman G, Morikami A, Jung J, Baskin TI, Carpita NC, Derbyshire P, McCann MC, Benfey PN. COBRA encodes a putative GPI-anchored protein, which is polarly localized and necessary for oriented cell expansion in Arabidopsis. Genes and Development 2001 May 1;15(9):1115-27.